reduction of serum cholesterol in hypercholesterolemic rats by guar gum

Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum

Objective: Several diseases are reported to be uncommon in those parts of the world where dietary fiber intakes are high, therefore, in this study; we evaluated the hypocholesterolemiceffects of a dietary fiber (guar gum) in hypercholesteromic rats. Materials and Methods: Rats were fed high-fat or a normal fed diet for 12-week then treated with 5% guar gum in their regime during a 28 days peri...

Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum

Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum

In the previous issue of AJP an article under the title of "Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum" was published (Samarghandian et al., 2011), which raised some question to be discussed more. In the “Animal Experimental Procedure” section, for induction of hypercholesterolemia, rats have been fed a chow supplemented with 18% corn oil. This diet is absolutely a ...

Guar gum and plasma cholesterol. Effect of guar gum and an oat fiber source on plasma lipoproteins and cholesterol in hypercholesterolemic adults.

The hypolipidemic effect of guar gum (GG, 15 g/day) was compared with that of an oat fiber source (OFS, 77 g/day). Both treatments supplied the same amount of total dietary fiber (11 g/day) and were taken with water three times a day for 3 weeks at mealtime. Thirteen free-living adult men and women participated in the study. Their total plasma cholesterol (TC) was 244 +/- 21 mg/dl (mean +/- SD)...

Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed.

BACKGROUND Secoisolariciresinol diglucoside (SDG) is a plant lignan isolated from flaxseed. Lignans are platelet-activating factor-receptor antagonists that would inhibit the production of oxygen radicals by polymorphonuclear leukocytes. SDG is an antioxidant. Antioxidants studied thus far are known to reduce hypercholesterolemic atherosclerosis. The objective of this study was to determine the...

Effect of Palatable Guar Gum Formulation on Serum Lipids

This clinical study reports that the ingestion of 15 gm of Guar gum daily for a period of one moth decreased the total serum cholesterol level by 9.4% and triglyceride level by 4%.